Scientifically Backed Advice

More then anectdotal evidence its Science

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Aging

The Pineal Aging Clock

Reversal of epigenetic aging and immunosenescent trends in humans

What Is Antagonistic Pleiotropy?

Yamanaka factors

Very low ATP/ADP ratios with aging of the natural death senescence mutant of Neurospora crassa

Pineal Cross Transplant

Noninvasive neonatal thymus graft into the axillary cavity extends the lifespan of old mice

The Mechanism of Programmed Aging: The Way to Create a Real Remedy for Senescence

DNA methylation age of human tissues and cell types

The Horvath Clock Measures Epigenetic Aging

An antagonistic pleiotropic gene regulates the reproduction and longevity tradeoff

Biophysics

ORNL researchers discover new state of water molecule

Lucia Light

DNA Charge Transport: From Chemical Principles to the Cell

Evidence about the power of intention

Mechanisms of Geomagnetic Field Influence on Gene Expression Using Influenza as a Model System: Basics of Physical Epidemiology

An Overview of Biofield Devices

Intermediate tunnelling–hopping regime in DNA charge transport

Observation of coherent delocalized phonon-like modes in DNA under physiological conditions

The Eternal Source Of Energy Of The Universe, Origin And Intensity Of Cosmic Rays

Thermal and non-thermal health effects of low intensity non-ionizing radiation: An international perspective

Brain Health

Early-Onset Dementia and Alzheimer's Rates Grow for Younger American Adults

New evidence for a human magnetic sense that lets your brain detect the Earth's magnetic field

Mental Health By the Numbers

Stem Cell Therapy & GcMAF For Autism & Neurological Disorders

Antipurinergic therapy for autism—An in-depth review

Cardio-Metabolic Health

High Cholesterol Induces Anaerobic Metabolism

Insulin and Insulin Resistance in Alzheimer's Disease

Circadian clocks and insulin resistance

Study Shows Walking an Hour a Day Achieves Greatest Longevity Benefit

Development of thymosin beta4 for treatment of patients with ischemic heart disease

Hepatocyte membrane potential regulates serum insulin and insulin sensitivity by altering hepatic GABA release

The Circadian Clock, Shift Work, and Tissue-Specific Insulin Resistance

Detox

Arsenic, Cadmium, Lead, and Mercury in Sweat: A Systematic Review

Metal resistance in Candida biofilms

Is there a role for charcoal in palliative diarrhea management?

Use of zeolite for removing ammonia and ammonia-caused toxicity in marine toxicity identification evaluations

Sauna Detoxification Of Metals, Pesticides And Chemicals: Addressing The Background Exposures And Increasing Health Problems Of An Industrial Society

High-Aluminum-Affinity Silica Is a Nanoparticle That Seeds Secondary Aluminosilicate Formation

Effect of long-term dietary supplementation with clinoptilolite on performance and selected serum biochemical values in dairy goats

Diet

Structure-function and application of plant lectins in disease biology and immunity

Lectins

Calorie Restriction Trial Rejuvenates Thymus and Extends Human Health Span

Gut Health

Changing gut bacteria through diet affects brain function, UCLA study shows

Human Skin, Oral, and Gut Microbiomes Predict Chronological Age

Melatonin-Mediated Colonic Microbiota Metabolite Butyrate Prevents Acute Sleep Deprivation-Induced Colitis in Mice

Gastrointestinal melatonin: localization, function, and clinical relevance

Human Gut Bacteria Are Sensitive to Melatonin and Express Endogenous Circadian Rhythmicity

Skin Exposure to Narrow Band Ultraviolet (UVB) Light Modulates the Human Intestinal Microbiome

Substitutes for Bear Bile for the Treatment of Liver Diseases: Research Progress and Future Perspective

Stable gastric pentadecapeptide BPC 157 in the treatment of colitis and ischemia and reperfusion in rats: New insights

Melatonin and Ulcerative Colitis: Evidence, Biological Mechanisms, and Future Research

Melatonin and the Gut: The Untold Connection

Immune Health

Immune System as a Sensory System

Béchamp or Pasteur? A Lost Chapter in the History of Biology

Newly Discovered ‘Potential Organ’ Described by Dr. Revici in 1961

Deep Breathing And The Lymphatic System

Rejuvenate Your Thymus Gland

The Immunoendocrine Thymus as a Pacemaker of Lifespan

Role of the thymus in programming of neuroendocrine functions

Pasteur: Plagiarist, Imposter

The Lipid Defense in Autoimmunity: A Case Study

Lymphatic System

Mast Cells and Melatonin

Focus on immune defenses: immune system, zinc and melatonin act together

Potential role of melatonin in autoimmune diseases

IgE and mast cells in allergic disease

Peptide-Based Treatment: A Promising Cancer Therapy

Melatonin

Melatonin as a mitochondria-targeted antioxidant: one of evolution's best ideas

The circadian pattern of melatonin and its positive relationship with progesterone in women

Melatonin Promotes Brain-Derived Neurotrophic Factor (BDNF) Expression and Anti-Apoptotic Effects in Neonatal Hemolytic Hyperbilirubinemia via a Phospholipase (PLC)-Mediated Mechanism

Melatonin protects mast cells against cytotoxicity mediated by chemical stimuli PMACI: possible clinical use

Melatonin and melatonin-progestin combinations alter pituitary-ovarian function in women and can inhibit ovulation

Melatonin protects endothelial progenitor cells against AGE-induced apoptosis via autophagy flux stimulation and promotes wound healing in diabetic mice

Melatonin pharmacokinetics following two different oral surge-sustained release doses in older adults

Reduced oxidative damage in ALS by high-dose enteral melatonin treatment

The Therapeutic Potential of Melatonin: A Review of the Science

Melatonin: Nature's most versatile biological signal?

Effects of melatonin in perimenopausal and menopausal women: a randomized and placebo controlled study

Melatonin in the colon modulates intestinal microbiota in response to stress and sleep deprivation

Melatonin in Early Nutrition: Long-Term Effects on Cardiovascular System

Melatonin exerts immunoregulatory effects by balancing peripheral effector and regulatory T helper cells in myasthenia gravis

Melatonin: shedding light on infertility? - a review of the recent literature

Melatonin rejuvenates degenerated thymus and redresses peripheral immune functions in aged mice

The effects of exogenous melatonin on the total sleep time and daytime alertness of chronic insomniacs: a preliminary study

The Therapeutic Effects of High-Dose Melatonin Administration

Toxicology of melatonin

Selectivity of melatonin pituitary inhibition for luteinizing hormone-releasing hormone

Role of melatonin in constitutional delayed puberty in boys

Melatonin Improves Fertility

Melatonin utility in neonates and children

Mental Health & Mood

What might explain the unhappiness epidemic?

Over 8 Million U.S. Children Now On Psychiatric Drugs

Number Of Children & Adolescents Taking Psychiatric Drugs In The U.S.

Mitochondria

Circadian rhythms in mitochondrial respiration

Mitochondrial functions and melatonin: a tour of the reproductive cancers

Mitochondria: Central Organelles for Melatonin′s Antioxidant and Anti-Aging Actions

Mitochondria Synthesize Melatonin to Ameliorate Its Function and Improve Mice Oocyte's Quality under in Vitro Conditions

Melatonin synthesis in and uptake by mitochondria: implications for diseased cells with dysfunctional mitochondria

Perspective: Cell danger response Biology—The new science that connects environmental health with mitochondria and the rising tide of chronic illness

Naviaux Cell Danger Biology & The Future Of Personalized Medicine

Melatonin, mitochondria, and the skin

Melatonin: A Mitochondrial Targeting Molecule Involving Mitochondrial Protection and Dynamics

Melatonin Mitigates Mitochondrial Meltdown: Interactions with SIRT3

Regeneration

Humans have salamander-like ability to regrow cartilage in joints

Peptides Bioregulator

Umbilical Cord Blood: A Unique Source of Pluripotent Stem Cells for Regenerative Medicine

Allograft Stem Cell Therapy

Human Umbilical Cord Tissue-Derived Mesenchymal Stem Cells (hUC-MSCs) for Autism and Multiple Sclerosis

Aging of lymphoid organs: Can photobiomodulation reverse age-associated thymic involution via stimulation of extrapineal melatonin synthesis and bone marrow stem cells?

Placental Cells and Tissues: The Transformative Rise in Advanced Wound Care

Universal DNA methylation age across mammalian tissues

Dissection of the Anti-Inflammatory Effect of the Core and C-Terminal (KPV) α-Melanocyte-Stimulating Hormone Peptides

Umbilical Cord Tissue as a Source of Young Cells for the Derivation of Induced Pluripotent Stem Cells Using Non-Integrating Episomal Vectors and Feeder-Free Conditions

Paracrine Signaling

Rejuvenation of degenerative thymus by oral melatonin administration and the antagonistic action of melatonin against hydroxyl radical-induced apoptosis of cultured thymocytes in mice

A summary of studies – BPC-157

The effect of tripeptide-copper complex on human hair growth in vitro

Sunlight & Circadian Rhythm

Fat cells can sense sunlight—not getting enough increases metabolic syndrome risk

Circadian control of the immune system

Effects of light on human circadian rhythms, sleep and mood

The Circadian Control of Skin and Cutaneous Photodamage

The myopia boom

Cancer and the Endogenous “Pineal Clock”: A Means of Early Diagnosis and Successful Treatment as Well as Prevention of Cancers

Non-visual effects of light: How to use light to promote circadian entrainment and elicit alertness

Intrinsic Photosensitivity Enhances Motility of T Lymphocytes

Benefits of Sunlight: A Bright Spot for Human Health

Avoidance of sun exposure is a risk factor for all-cause mortality: results from the Melanoma in Southern Sweden cohort

REV-ERB in GABAergic neurons controls diurnal hepatic insulin sensitivity

Restoring Deep, Slow Wave Sleep to Enhance Health and Increase Lifespan

Trauma

The Effects of Prenatal Stress on Child Behavioural and Cognitive Outcomes Start at the Beginning

How to Target Treatment to Help Patients Reclaim Their Lives After Trauma

About the CDC-Kaiser ACE Study

Adverse Childhood Experiences (ACEs) Preventing early trauma to improve adult health

Ayahuasca Stimulates the Birth of New Brain Cells

Why the Vagal System Holds the Key to the Treatment of Trauma

Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults

Child Abuse and Neglect: Breaking the Intergenerational Link

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Research Papers

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